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23,24,25,26 Besides, prematurity, defined as birth before 37 weeks of gestation (GA), represents a major public health concern as it affects between 5-18% of births worldwide, 27 is a leading cause of neonatal and under-5 years mortality, 28 and increases the risk of disability among those who survive

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Our results also indicate that senescent chondrocytes present a larger and flatter cell shape, which is consistent with a previous study (Cha et al., 2013)